Infertility, Diabetes, Obesity and the Mystery of PCOS

Polycystic ovarian syndrome (PCOS), in short, is a condition in which a woman’s hormones are out of balance. The condition is frequently associated with weight gain in a young women. This results in androgenization (acne, excessive facial and body hair), menstrual irregularities and infertility. PCOS is common, affecting as many as 1 out of 10 women. It is thought to be one of the leading causes of female subfertility and the most frequent endocrine problem in women of reproductive age.

Besides the disturbances in the sex hormones, the sinister feature of the syndrome is insulin resistance and obesity, which lead to diabetes. In fact, as many as 1 in 4 women with PCOS has diabetes. As a result of these metabolic disturbances, women with PCOS have a higher risk of cardiovascular event in their lifetime. Although termed as an ‘ovarian’ syndrome, the underlying pathology is not restricted to the ovaries. Often, there is a conglomeration of endocrine and metabolic problems in a woman with PCOS. These hormonal and metabolic disturbances can be amenable to treatment, with restoration of menstrual cycles and fertility in many instances.

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Thyroid Supplements – Caution!

Thyroid diseases are common. In the US, more than 12% of Americans will develop a thyroid disorder during their lifetime. Many people with vague symptoms like feeling sluggish or weight gain, turn to dietary supplements that promise to jump-start metabolism by bolstering their thyroids with a mixture of vitamins and minerals. However these over-the-counter products may also contain thyroid hormones that should only be dispensed by prescription. In some cases these supplements contain amounts of thyroid hormone as high or higher than delivered by prescription medications. Indiscriminately use of such supplements that contain thyroid hormone may lead to serious side effects including nervousness, insomnia, heart problems and thinning of bone.

In Singapore, such products are not widely seen or available as yet. However given the ease of online orders, it might be relatively easy for these products to be obtained from overseas. Anyone with suspected thyroid disorders should consult a physician for a proper work up rather than relying on supplements to resolve their symptoms.

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