The National Institute for Health and Care Excellence (NICE) recommends that more people should be put on cholesterol-lowering statin drugs to protect them against heart attacks and strokes. Some patients remained reluctant to take statins despite the doctors’ advice, for fear of side effects. However side effects from statins which include liver and muscle problems are rare, and usually reversible upon cessation of the drug. The benefits of statin extend beyond simply lowering cholesterol and improving metabolic profile. Studies have shown in a vascular event, patients who are on statins tend to have a better survival rate. Patients should actively screened for cholesterol problems and speak to their doctors about statins so that they can make a well informed decision about their treatment and health.